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Applying one-molecule optical and AFM imaging and power-spectroscopy techniques, we request to unravel the mechanistic components of the framework and dynamics of chromosomes. Our investigation interests involve:

You frequently get involved in conversations about science and faith. You may have also composed several textbooks on the subject. Don’t you are convinced sooner or later We're going to know almost everything and that God’s position will probably be about?

, Groningen scientists existing the effects in their endeavours to make labs much more sustainable and provide methods for other labs. 

Sad to say, For many years just after Iijima’s report, the production of cleanse nanotubes was cumbersome. In 1996, nevertheless, the team of Richard Smalley at Rice University managed to supply one-walled carbon nanotubes at higher produce. Soon right after, I contacted Smalley, and we made a decision to join forces to evaluate the transportation through a solitary carbon nanotube.

We develop issue-of-treatment diagnostics check of neglected tropical illnesses within source-restricted settings, dependant on Crspr/Cas9 detecting of pathogen’s DNA in overall body fluids.

SMC complexes can pass physical roadblocks larger than their ring sizing, indicating a nontopological system for DNA loop extrusion

A lot of linked developments adopted, wherever our team recognized unique transistor variants which include one-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into small evidence-of-basic principle Digital circuits.

Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in grey, the rim with the pore is highlighted in red, and also a 3D rendering in the movement from the DNA rod is exhibited.

2003, shown the main biosensors built away from a carbon nanotube; solved the construction and mechanism of DNA maintenance proteins; and cees dekker discovery of a new system for fabricating good-condition nanopores for DNA translocation

Bulk-surface area coupling identifies the mechanistic link involving Min-protein styles in vivo As well as in vitro

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Nanoscientist Cees Dekker is really an amiable and flamboyant male who appears A lot younger when compared to the sixty two several years he truly is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not one to squander time. He will take his time, but no more than vital.

Developments in nanotechnology while in the nineteen nineties designed setting up Digital equipment from one molecules a risk. Cees Dekker recounts how his workforce created a room-temperature transistor based on a single carbon nanotube.

Supercoiling-dependent DNA binding: quantitative modeling and apps to bulk and solitary-molecule experiments

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